Xgeva 120mg Injection contains the active ingredient Denosumab, a medication used primarily to treat osteoporosis, a condition where bones become weakened and brittle. It is also prescribed to prevent bone complications in patients with certain types of cancer, such as multiple myeloma or bone metastases.
Xgeva works by inhibiting a protein called RANK ligand, which plays a key role in the breakdown of bone tissue. By blocking this protein, Xgeva helps increase bone density and reduces the risk of fractures, particularly in postmenopausal women with osteoporosis and in cancer patients who experience bone loss due to their condition.
For patients with moderate renal impairment, close monitoring of kidney function may be required. It is essential for individuals undergoing treatment with Xgeva to maintain adequate calcium and vitamin D levels, as these nutrients are necessary for effective treatment.
Xgeva should not be used in individuals who have known hypersensitivity or allergic reactions to its components. It is contraindicated in children and adolescents, as its safety and effectiveness in individuals under 18 years old have not been established. Additionally, caution is needed in patients with pre-existing hypoparathyroidism (low parathyroid hormone levels).
As with any medication, it is important for patients to discuss their medical history and current health conditions with their healthcare provider before starting Xgeva treatment.